Effectiveness of low-tube current for reducing radiation dose in cerebral CT perfusion

Introduction Objective: This study aims to investigate the reduction of radiation dose in cerebral CT perfusion by lower low-tube current. Material and methods Two hundred patients, who underwent non-contrast computed tomography (CT) perfusion, were randomized into four groups according tube current contrast media (CM) concentration: group A (60 mAs, 320 mgI/ml), B 370 C (100 D mgI/ml). Among these groups, index (CTDIvol), length product (DLP) effective (ED) was calculated. The quantitative image comparison included maximum enhancement, noise, signal-to-noise ratio (SNR), blood volume (CBV), flow (CBF), mean transit time (MTT) from five regions interests (ROIs). Results Ranging 100 mAs 60 achieved 40% CTDIvol, DLP ED, when compared with D. Both enhancement noise all ROIs higher B, (P<0.05). CBV values D, quality (IQ) each maps met requirements for imaging diagnosis. Conclusions led a without sacrificing quality.